您好,欢迎访问知识创客N-免费论文下载

上传文档

当前位置:首页 > 学术论文 > 国外论文 > Cellulose membrane modified with LED209 as an antibacterial and

Cellulose membrane modified with LED209 as an antibacterial and

二扫码支付 微信
二扫码支付 支付宝

还剩... 页未读,继续阅读

免费阅读已结束,点击付费阅读剩下 ...

ⓞ 0 知识点,已有0人购买

免费阅读

阅读已结束,您可以下载文档离线阅读

ⓞ 0 知识点,已有0人下载

免费下载
文档简介:

CarbohydratePolymers252(2021)117138Availableonline28September20200144-8617/©2020ElsevierLtd.Allrightsreserved.CellulosemembranemodifiedwithLED209asanantibacterialandanti-adhesionmaterialZongbaoZhoua,ZixuanDonga,LeiWangb,RijianSonga,NaibinMeia,TaoChena,LeiLuoa,QiangDinga,XiaoyingWanga,ShunqingTanga,*aBiomedicalEngineeringInstitute,JinanUniversity,Guangzhou,510632,PRChinabDepartmentofPharmacology,UtrechtInstituteforPharmaceuticalSciences,UtrechtUniversity,3568CG,Utrecht,theNetherlandsARTICLEINFOKeywords:SurfacemodificationLED209cellulosemembraneclickreactionanti-adhesionactivityEHECABSTRACTBacterialadhesioninfectioncausedbymedicalmaterialsinclinicalapplicationhasbecomeaseriousthreat,anditurgentlyneedsnewstrategiestodealwiththeseclinicalchallenges.Inthiswork,LED209,ahighlyselectivehistidinesensorkinaseinhibitorofGram-negativebacteria,wascovalentlyattachedoncellulosemembrane(CM)viaclickreaction.Thedataofcontactanglemeasurements,ATR-FTIRandX-rayphotoelectronspectroscopyconfirmedthesuccessfulsynthesisofLED-CM.Inaddition,theresultsofantibacterialactivityofthemembranesshownthatLED-CMexhibitedexcellentanti-adhesionabilitytoEnterohemorrhagicEscherichiacoli(EHEC),andsignificantlyreducedtheformationofbacterialbiofilm.Importantly,LED-CMwasabletorepresstheexpressionofvirulencegenesinEHEC.Furthermore,LED209-functionalizedcellulosemembraneindicatednocytotoxicitytomammaliancells.Hence,ourpresentworkdemonstratedthatCMmodifiedwithLED209possessedmarkedlyanti-adhesionactivityagainstEHEC,whichoff

文档达人

8641篇文档

评论

发表评论
< /10 > 免费下载 ⓞ 0 知识点

Powered by DS文库

Copyright © 知识创客N-免费论文下载 All Rights Reserved. 蜀ICP备2020030266号-1
×
保存成功
$urls = array( 'http://www.example.com/1.html', 'http://www.example.com/2.html', ); $api = 'http://data.zz.baidu.com/urls?site=https://www.fabuzhijia.cn&token=SLuZ3R4dqpKJoC8K'; $ch = curl_init(); $options = array( CURLOPT_URL => $api, CURLOPT_POST => true, CURLOPT_RETURNTRANSFER => true, CURLOPT_POSTFIELDS => implode("\n", $urls), CURLOPT_HTTPHEADER => array('Content-Type: text/plain'), ); curl_setopt_array($ch, $options); $result = curl_exec($ch); echo $result;